PRINCIPLE OF INHERITANCE AND VARIATION

GENETIC DISORDERS

Genetic disorders is a disease that is caused by an abnormality in an individual's DNA. Genetic disorders are mainly of two types: Chromosomal disorder, cause by an abnormality in the chromosomes of individual. Mendelian disorder; caused by mutation or alteration in the single gene.

MENDELIAN INHERITANCE

Gregor Jhon Mendel conducted hybridization experiments on garden peas(Pisum sativum) and proposed laws of inheritance.He proposed three laws of inheritance;law of Dominance, law of segregation, law of independent assortment.

CHROMOSOMAL THEORY OF INHERITANCE

Chromosomal theory of inheritance states that genes are located on specific site on chromosomes which are responsible for the inheritance of characters. Linkage and crossing over, polygenic inheritance, pleiotropy are based on this theory. Sex determination and mutation are the phenomenon which which influence the inheritance pattern of organisms.

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