MOLECULAR BASIS OF INHERITANCE

DNA FINGERPRINTING

DNA fingerprinting is the technique where DNA sequences of two individuals are compared. It is widely used in the identification of paternity.

GENETIC CODE

Genetic code is a triplet sequences of bases that codes for particular amino acids that further helps in protein synthesis. Mutations are sudden change; it can be point mutation or frame shift mutation.

GENETIC MATERIAL

Ribonucleic acid and deoxyribonucleic acid are nucleic acids which are differ from each other in the presence of thymine in DNA and uracil in RNA.

TRANSCRIPTION

Transcription is a process where DNA is converted into RNA by the help of RNA polymerase. Information of DNA is copied into mRNA for the synthesis of protein. After RNA synthesis it is modified further by the process of post transcriptional modification.

TRANSLATION

Translation is a process of synthesis or formation of protein from mRNA. Three process like initiation, elongation and termination are involve in translational process.

REPLICATION

Replication is a process of copying of DNA. Messelson and stahl done an experiment to prove that DNA is of semi-conservative in nature where one strand is antisense or template strand and other strand is sense or leading strand.

SEARCH OF GENETIC MATERIAL

Genetic material was searched by the help of following experiments. Frederick Griffith done an experiment on streptococcus pneumoniae to recovered genetic material. Avery, Mccarty and Macleod identify the biochemical nature of genetic material.

PACKAGING OF DNA

DNA is tightly packed in the nucleus of every cell. DNA wraps around special proteins called histones, which form loops of DNA called nucleosomes.

REGULATION OF GENE EXPRESSION

Expression of genes can be regulated by lac operon model which was proposed by Jacob and Monad. The regulation of lac operon by repressor is known as negative regulation.

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