Gout is a kind of arthritis caused by a build up of uric acid crystals in the joints. Uric acid is a breakdown product of purines that are part of many foods that we eat. An abnormality in handling of uric acid and crystallization of these compounds in joints can cause attack of painful arthritis, kidney stones and blockage of the kidney filtering tubules with uric acid crystals, leading to kidney failure.
The small joint at the base of the big toe is the most common site for an attack. Other joints that can be affected include ankles, knees, wrists, fingers and elbows. The signs and symptoms of gout almost always occur suddenly and often at night. This includes:
When you experience sudden or intense pain in a joint, go to doctor. Gout that goes untreated can lead to worsening pain and joint damage. Seek medical care immediately if we have a fever and a joint is hot and inflamed which can be a sign of infection.
There are a variety of factors that can play a role in causing it. There are a variety of factors that can play a role in causing it. Certain conditions such as blood and metabolic disorders can cause our body to produce too much uric acid. Drinking too much alcohol can also lead to excess uric acid. Certain foods can cause gout when we eat too much of them. These include shellfish; Red meat, organ meat, sweet juice and salt.
We can also develop gout if our body is not eliminating uric acid properly. If we are dehydratetd or starved, it can make it difficult for our body to excrete uric acid. This causes it to build up as deposits in our joints. Some disease or disorders such as kidney or thyroid problem can also impair our body ability to excrete uric acid. Certain medications include diuretics and immunnosuppresive fungal medications such as cyclosporine.
Stages of Gout:
There are four stages of gout:
Risk factor for Gout:
Diagnosis of Gout:
On the basis of review of medical history or physical exams and other symptoms, doctor can make a diagnosis. Doctor can diagnose disease on the basis of description of joint pain, how often we experience intense pain in the joints and how red or swollen the area. Doctor can also conduct a test to check for build up of uric acid in the joints. They will collect a sample of fluid from our joint to learn if it contains uric acid. Gout can also be analysed by another technique:
Treatment of Gout:
In most cases regular examination by doctor can treat this disease, if we have severe complications or chronic tophaceous gout is develop then doctor can refer the patient to rheumatologist. These types of doctors are specialized in arthritis. Doctor prescribed treatment plan will depends on the stages and severity of gout. Doctors may prescribe:
Complications of Gout:
Gout is the disease if it is left untreated then it can cause tophi to develop near the inflamed joints. This can also lead to arthritis, a painful condition in which the joints get permanently damaged or swollen.
Gout can be prevented by following factors:
Skeletal system is made up of bones and cartilage. It is oftwo types; axial and appendicular skeleton. Skeletal system performs functions like;support, movement, protection,sexual dimorphism, mineral haemostasis.
Movement is one of the significant features of all living organism. Movement involves four basic mechanism:amoeboid, ciliary, flagellar and muscular. There are three types of muscles that helps in locomotion; skeletal, visceral and cardiac muscles.
Muscle cells are specialized for contraction which also helps in bodily processes such as respiration and digestion.Sarcomere must shortens for a muscle cell to contract.The sliding filament model defines the concept of muscle contraction.
Joints is a point of articulation where two or more bones meet. The motions like spin, swing, approximation and gliding movements are made possible by joints. Joints can be classified as fibrous, cartilaginous and synovial joints. Pivot and hinge joints are synovial joints.
Tetany is a series of symptoms characterized bypainful muscles cramps that derives from enhanced neuro-muscular excitability due to hypocalcemia hypomagnesemia or alkalosis. There are three types of tetany; hypocalcaemic, grass and latent tetany.